Lipid-based nanostructures as a strategy to enhance curcumin bioaccessibility: Behavior under digestion and cytotoxicity assessment
نویسندگان
چکیده
Acknowledgments Raquel F. S. Goncalves acknowledge the Foundation for Science and Technology (FCT) her fellowship (SFRH/BD/140182/2018) . This study was supported by under scope of Project PTDC/AGRTEC/5215/2014, strategic funding UIDB/04469/2020 unit BioTecNorte operation (NORTE-01-0145-FEDER-000004) funded European Regional Development Fund Norte2020Programa Operacional do Norte. Funding from INTERFACE Programme through Innovation, Circular Economy (FITEC) iNova4Health, a program also financially Fundacao para Ciencia eTecnologia, is gratefully acknowledged.
منابع مشابه
Carotenoid bioaccessibility and the relation to lipid digestion: A kinetic study.
The micellar incorporation of carotenoids (lycopene, α- and β-carotene) and lipid digestion products (free fatty acids, FFAs, and monoacylglycerides, MAGs) during in vitro digestion of oil-in-water emulsions was investigated by a kinetic approach. A fractional conversion model could adequately describe the hydrolysis of triacylglycerides, formation of FFAs and MAGs, and micellar incorporation o...
متن کاملNanostructured lipid systems as a strategy to improve the in vitro cytotoxicity of ruthenium(II) compounds.
Tuberculosis is an ancient disease that is still present as a global public health problem. Our group has been investigating new molecules with anti-TB activity. In this context, inorganic chemistry has been a quite promising source of such molecules, with excellent results seen with ruthenium compounds. Nanostructured lipid systems may potentiate the action of drugs by reducing the required do...
متن کاملa paradigm shift away from method-wise teaching to strategy-wise teaching: an investigation of reconstructive strategy versus communicative strategy
چکیده: هدف اصلی این مطالعه ی توصیفی تحقیقی در حقیقت تلاشی پساروش-گرا به منظور رسیدن به نتیجه ای منطقی در انتخاب مناسبترین راهکار آموزشی بر گرفته از چارچوب راهبردی مطرح شده توسط والدمر مارتن بوده که به بهترین شکل سازگار و مناسب با سامانه ی آموزشی ایران باشد. از این رو، دو راهکار آموزشی، راهکار ارتباطی و راهکار بازساختی، برای تحقیق و بررسی انتخاب شدند. صریحاً اینکه، در راستای هدف اصلی این پژوهش، ر...
15 صفحه اولMitochondrial-Targeted Curcuminoids: A Strategy to Enhance Bioavailability and Anticancer Efficacy of Curcumin
Although the anti-cancer effects of curcumin has been shown in various cancer cell types, in vitro, pre-clinical and clinical studies showed only a limited efficacy, even at high doses. This is presumably due to low bioavailability in both plasma and tissues, particularly due to poor intracellular accumulation. A variety of methods have been developed to achieve the selective targeting of drugs...
متن کاملthe effectiveness of strategy-based instruction in teaching english as a second or foreign language: a meta-analysis of experimental studies
a large number of single research studies on the effects of strategy-based instruction (sbi) in teaching english as a foreign or second language has been conducted so far. however, the lack of a comprehensive meta-analysis targeting the effectiveness of english language sbi is observed. moreover, the findings of experimental studies regarding the context of the english language, proficiency lev...
ذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Food Research International
سال: 2021
ISSN: ['0963-9969', '1873-7145']
DOI: https://doi.org/10.1016/j.foodres.2021.110278